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Catalog / Neuropeptide / Selank
Neuropeptide

Selank 10mg

Tuftsin Analog · TKPRPGP

Selank is an investigational synthetic heptapeptide and tuftsin analogue with the sequence TKPRPGP. Also known as TP-7, it is a peptide studied for its interactions with GABAergic signaling, neurotransmitter pathways, neuroinflammation, and gene expression. Current research includes neuroscience, neurobiology, cognitive research, stress-response pathways, immune signaling, and molecular biology.

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Compound information

Chemical & structural properties
What it is

What is the Peptide?

A seven-amino-acid peptide built from tuftsin, a natural immune-signaling molecule, extended for stability. Developed in Russia, it is studied as an anxiolytic that works through the GABA system while keeping the immune-modulating properties of its parent peptide.

Tuftsin analogGABAergic researchResearch grade
ClassAnxiolytic / immunomodulatory peptide
OriginTuftsin (Thr-Lys-Pro-Arg) analog
FormLyophilized powder
UseResearch use only
Molecular profile

Structure

TypeSynthetic heptapeptide (7 aa)
CAS Number129954-34-3
Molecular Weight751.87 g/mol
SequenceThr-Lys-Pro-Arg-Pro-Gly-Pro
FormulaC33H57N11O9
PubChem Database · CID 11765600
Storage requirements

Stability information

Store coldProtect from lightKeep dry
Lyophilized (powder)
−20 °C · stable
Reconstituted
2–8 °C · short-term
Overview

Product overview

A tuftsin-derived anxiolytic research peptide supplied for laboratory evaluation at a ≥99% HPLC analytical standard.

Technical overview

Selank extends the natural immune tetrapeptide tuftsin, Thr-Lys-Pro-Arg, with a Pro-Gly-Pro tail that sharply improves its stability and duration. The addition preserves tuftsin's immune activity while adding pronounced effects on the GABA system, the basis of its study as a non-sedating anxiolytic.

It is produced by solid-phase synthesis and preparative purification, then released against a lot-matched Certificate of Analysis carrying HPLC purity and LC-MS identity.

Research applications

Selank is studied at the intersection of the nervous and immune systems. Common laboratory work includes GABA-receptor modulation and inhibitory-current assays in hippocampal neurons, anxiety and stress behavioral models, enkephalin-degradation and enkephalinase studies, and cytokine and interferon gene-expression research drawn from its tuftsin lineage.

For Research Use Only · Not for human or veterinary use

Kylo Peptides supplies this compound as a reference material for scientific inquiry. All applications must be conducted by qualified professionals in controlled laboratory environments. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

FAQ

Frequently Asked Questions

Tuftsin is a natural four-amino-acid immune peptide, Thr-Lys-Pro-Arg. Selank is tuftsin with a Pro-Gly-Pro tail added to the end. That extension keeps tuftsin's immune-signaling activity but greatly increases how long the peptide survives in the body, turning a short-lived immune fragment into a more stable research compound.

Its most studied route is the GABA system. Selank behaves as a positive modulator of GABA signaling, the brain's main inhibitory pathway, which is the basis of its study as an anxiolytic. Research also points to a second route, the stabilization of enkephalins through reduced enkephalinase activity.

Both are Russian heptapeptides that share the Pro-Gly-Pro stabilizing tail, but they come from different parents and do different jobs. Selank is built from the immune peptide tuftsin and is studied mainly as an anxiolytic with immune activity. Semax is built from an ACTH fragment and is studied mainly for BDNF-driven neuroprotection.

Testing confirms ≥99% by HPLC on every lot, with mass spectrometry establishing identity. Independent third-party analysis clears each batch before release, and the certificate for a given lot can be retrieved using the number marked on the vial.

Keep it cold and dry. The lyophilized powder holds at −20 °C sealed and out of light, with −80 °C better for long storage. After reconstitution, the solution belongs at 2 to 8 °C, should be used within a validated window, and should not be cycled repeatedly through freezing.

No. Kylo supplies Selank as a characterized reagent for in vitro laboratory research only. It is not formulated or labeled for use in humans or animals, and it is provided strictly to qualified researchers for controlled experimental work.

Backed By A Lot-Matched COA

Every Selank order is tied to a certificate of analysis matched to the exact lot in your vial.

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