Ipamorelin 10mg & 5mg
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂. It acts primarily through the ghrelin/growth hormone secretagogue receptor (GHSR-1a) and is studied in growth hormone signaling, GHSR pharmacology, pituitary signaling, peptide-receptor interactions, and endocrine research, with particular interest in its selective stimulation of growth hormone release compared with other growth hormone–releasing peptides.
Compound information
What is the Peptide?
A five-amino-acid peptide designed to mimic ghrelin and switch on its receptor, GHS-R1a. Research values it for selectivity: it prompts growth-hormone release in laboratory models while leaving cortisol, prolactin, and other pituitary hormones largely untouched, unlike broader secretagogues.
Structure
Stability information
Product overview
A selective growth-hormone secretagogue supplied for laboratory evaluation at a ≥99% HPLC analytical standard.
Technical overview
Ipamorelin is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys, built around two non-standard residues — aminoisobutyric acid and D-2-naphthylalanine — which confer stability and receptor selectivity. It binds the growth hormone secretagogue receptor and triggers calcium signaling linked to growth-hormone release.
It is produced by solid-phase synthesis and preparative purification, then released against a lot-matched Certificate of Analysis carrying HPLC purity and LC-MS identity.
Research applications
Laboratories apply ipamorelin as a selective probe for GHS-R1a pharmacology. Common work covers receptor binding and Gq/PLC calcium-signaling assays in receptor-expressing cells, structure-activity studies isolating GHS-R signaling from broader secretagogue effects, and rodent models examining pituitary hormone release, bone formation, and gastric motility.
Kylo Peptides supplies this compound as a reference material for scientific inquiry. All applications must be conducted by qualified professionals in controlled laboratory environments. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Researched Together
Frequently Asked Questions
Its defining trait is a clean signal. Where many growth-hormone secretagogues also raise cortisol, prolactin, or ACTH, ipamorelin acts almost solely on the ghrelin receptor to prompt growth-hormone release. That narrow activity makes it a useful tool for studying GHS-R1a signaling without interference from other pituitary pathways.
Kylo ipamorelin is supplied at ≥99% purity by HPLC, with identity confirmed through LC-MS. Every lot passes independent third-party testing before it ships, and the matching certificate is published against the lot number printed on the vial.
Ipamorelin carries CAS number 170851-70-4 and the development code NNC 26-0161. Its molecular formula is C38H49N9O5, with a molecular weight of about 711.86 g/mol and a five-residue sequence of Aib-His-D-2-Nal-D-Phe-Lys.
Keep the lyophilized powder at −20 °C, sealed and dry, out of direct light, with −80 °C preferred for long-term storage. It dissolves readily in water once reconstituted, after which the solution should be refrigerated at 2 to 8 °C and used within a validated window.
The two act on separate receptors. Ipamorelin works through the ghrelin receptor as a secretagogue, while CJC-1295 mimics growth-hormone-releasing hormone at the GHRH receptor. Because their mechanisms complement each other, researchers frequently study them as a pair, which is why the two appear together as a combined blend.
No. Kylo ipamorelin is intended for in vitro laboratory research only. It is not formulated, packaged, or labeled for human or veterinary use, and it is supplied strictly as a reference material for qualified researchers.
Backed By A Lot-Matched COA
Every ipamorelin order is tied to a certificate of analysis matched to the exact lot in your vial.
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