GHK-Cu 50 & 100mg
GHK-Cu is a naturally occurring copper-binding tripeptide consisting of glycine, histidine, and lysine complexed with copper (Cu²⁺). GHK peptide naturally occurs in human plasma, saliva, and urine and has a high affinity for copper. It is widely studied in copper-binding, collagen synthesis, extracellular matrix remodeling, fibroblast activity, cellular signaling, antioxidant, anti-inflammatory, and tissue-repair research.
Certificate of Analysis
Compound information
What is It?
The copper complex of the tripeptide glycyl-histidyl-lysine, discovered in human plasma by Loren Pickart in 1973. It binds copper with high affinity and shuttles it into cells, where the metal drives enzymes tied to collagen and connective-tissue formation. Plasma levels drop with age.
Peptide Structure
Stability information
Product overview
A plasma-derived copper tripeptide supplied for laboratory evaluation at a ≥99% HPLC analytical standard.
Technical overview
GHK-Cu pairs the tripeptide glycyl-histidyl-lysine with copper(II) in a one-to-one complex, a form in which the metal is central to the molecule's activity. The peptide chelates copper and transports it into cells, supplying copper-dependent enzymes such as lysyl oxidase, which build collagen and elastin.
It is supplied as a stable lyophilized powder and released against a lot-matched Certificate of Analysis carrying HPLC purity and identity confirmation.
Research applications
GHK-Cu appears widely in skin, wound, and matrix research. Typical laboratory work includes collagen and elastin synthesis assays in dermal fibroblasts, glycosaminoglycan and proteoglycan expression studies, wound-closure and tissue-remodeling models, antioxidant and anti-inflammatory panels, and hair-follicle research, with the copper-bound form used where the metal is integral to activity.
Kylo Peptides supplies this compound as a reference material for scientific inquiry. All applications must be conducted by qualified professionals in controlled laboratory environments. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Researched Together
Frequently Asked Questions
The copper is the active heart of the molecule. GHK, on its own, binds copper tightly and transports it into cells, where the metal activates enzymes such as lysyl oxidase that cross-link collagen and elastin. Most tissue-remodeling research uses the copper-bound form for that reason, since the metal is integral to the effect.
Kylo GHK-Cu is supplied at ≥99% purity by HPLC, with identity confirmed by analytical methods. Each lot passes independent third-party testing before release, and the certificate for that lot is published against the number printed on the vial.
GHK is the metal-free tripeptide glycyl-histidyl-lysine, with a molecular weight of 340.38 g/mol. GHK-Cu is that same peptide pre-complexed with copper, near 403.93 g/mol. The two are not interchangeable in every assay, since many classic remodeling activities depend on the presence of copper.
Keep the lyophilized powder frozen at −20 °C, sealed, dry, and out of light, with −80 °C preferred for long-term holding. Once reconstituted in water, refrigerate the solution at 2 to 8 °C, use it within a validated window, and keep it away from strong reducing agents that can disturb the copper.
The interest traces back to a specific observation: circulating GHK levels are high in youth and fall steadily with age. That decline, paired with the peptide's role in collagen and matrix formation, is what first drew researchers to study whether supplying GHK-Cu could restore some of that remodeling activity in laboratory models.
No. This peptide is intended for in vitro laboratory research only. It is not formulated, packaged, or labeled for human or veterinary use and is supplied strictly as reference material for qualified researchers.
Backed By A Lot-Matched COA
Every GHK-Cu order is tied to a certificate of analysis matched to the exact lot in your vial.
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