Epitalon 10mg
Epitalon is a synthetic tetrapeptide composed of alanine, glutamic acid, aspartic acid, and glycine (Ala-Glu-Asp-Gly / AEDG), originally developed from the amino acid composition of Epithalamin, a pineal gland extract. It is studied in pineal gland biology, melatonin regulation, telomerase and telomere research, antioxidant activity, neuroendocrine signaling, neuroprotection, cellular aging, and longevity research.
Compound information
What is the Peptide?
A four-amino-acid peptide built to reproduce the activity of epithalamin, a natural extract from the pineal gland. Developed in Russia by Vladimir Khavinson, it is studied mainly for its reported ability to switch on telomerase, the enzyme that maintains the protective caps on chromosomes.
Structure
Stability information
Product overview
A pineal-derived telomerase research tetrapeptide supplied for laboratory evaluation at a ≥99% HPLC analytical standard.
Technical overview
Epitalon is the synthetic tetrapeptide Ala-Glu-Asp-Gly, designed within Vladimir Khavinson's peptide-bioregulator program to mirror epithalamin, a peptide complex from the pineal gland. Its most studied reported activity is the induction of telomerase and lengthening of telomeres in cultured cells, alongside effects on gene expression and melatonin signaling.
It is produced by solid-phase synthesis and preparative purification, then released against a lot-matched Certificate of Analysis carrying HPLC purity and LC-MS identity.
Research applications
Epitalon is used chiefly in cellular-aging and gene-regulation research. Common laboratory work includes telomerase-activity and telomere-length assays in cultured human cells, hTERT gene-expression studies, circadian and melatonin-signaling models, and animal lifespan and oncostatic research drawn largely from the original Khavinson literature.
Kylo Peptides supplies this compound as a reference material for scientific inquiry. All applications must be conducted by qualified professionals in controlled laboratory environments. It has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Frequently Researched Together
Frequently Asked Questions About Epithalon
Its most reported activity is switching the enzyme on. Telomerase maintains telomeres, the protective ends of chromosomes that shorten each time a cell divides. In cultured human cells, epithalon has been reported to raise telomerase activity and lengthen telomeres, which is the basis of most research interest in the peptide.
Yes. The two spellings, along with epithalone, are just different transliterations of the same Russian name for the tetrapeptide Ala-Glu-Asp-Gly. They refer to one identical compound with the same CAS number and structure, so a certificate under either spelling describes the same peptide.
It was developed in the 1980s and 1990s by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology. It is a synthetic stand-in for epithalamin, a natural peptide complex extracted from the pineal gland, and belongs to a broader family of short peptide bioregulators from that research program.
Each lot is verified at ≥99% by HPLC, with mass spectrometry confirming identity. Independent third-party testing clears every batch before it ships, and the certificate for a given lot can be pulled up by the number printed on the vial.
Cold and dry throughout. Hold the lyophilized powder at −20 °C, sealed and out of light, with −80 °C better for long storage. After reconstitution, keep the solution at 2 to 8 °C, use it within a validated window, and avoid repeated freeze-thaw cycles.
Worth understanding clearly: most published epithalon research comes from a single research group, and the compound has not gone through large, independent randomized trials. The telomerase and aging findings are real published results, but they sit on a narrower evidence base than more widely replicated compounds, which is important context for any research use.
No. Kylo supplies epithalon as a characterized reagent for in vitro laboratory research only. It is not formulated or labeled for use in humans or animals, and it is provided strictly to qualified researchers for controlled experimental work.
Backed By A Lot-Matched COA
Every epithalon order is tied to a certificate of analysis matched to the exact lot in your vial.
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